Culture media additives for bioreactors

Details Culture media additives for bioreactors Culture media additives for bioreactors

C - Chemistry, Metallurgy

12

N

C12N 5/00 (2006.01) C12M 3/00 (2006.01)

Patent

CA 2163618

A hollow fiber bioreactor culture medium which contains a stabilized hemoglobin or a perfluorochemical emulsion is described. The culture medium mediates oxygen demand and utilization. Efficiency of the bioreactor is enhanced so that novel hollow fiber and stirred tank cell culture system configurations, equipment and methods are enabled.

On décrit un milieu de culture destiné à des bioréacteurs à fibres creuses, qui contient de l'hémoglobine stabilisée ou une émulsion d'un composé perfluoré. Le milieu de culture favorise l'absorption et l'utilisation de l'oxygène. L'efficacité du bioréacteur est améliorée. On obtient ainsi de nouvelles configurations de systèmes, de nouveaux équipements et de nouveaux procédés de culture de cellules faisant appel à des fibres creuses et à des réacteurs agités.

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