Culture medium containing kinase inhibitors, and uses thereof

Details Culture medium containing kinase inhibitors, and uses thereof Culture medium containing kinase inhibitors, and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 5/02 (2006.01)

Patent

CA 2645170

Pluripotent cells are maintained in a self-renewing state in serum-free culture medium comprising a MEK inhibitor, a GSK3 inhibitor and, optionally, an antagonist of an FGF receptor. Pluripotent cells are also maintained in a self-renewing state in serum-free culture medium comprising a MEK inhibitor and an antagonist of an FGF receptor.

Des cellules pluripotentes sont maintenues en état d'auto-renouvellement dans un milieu de culture sans sérum comprenant un inhibiteur de MEK, un inhibiteur de GSK3 et, éventuellement un antagoniste d'un récepteur FGF. Des cellules pluripotentes sont aussi maintenues en état d'auto-renouvellement dans un milieu de culture sans sérum comprenant un inhibiteur MEK et un antagoniste d'un récepteur FGF.

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