Cultured cell construct which contains spheroids of cultured...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/071 (2010.01) A61L 27/38 (2006.01) C12M 3/00 (2006.01) C12Q 1/00 (2006.01) C12N 11/00 (2006.01)

Patent

CA 2454807

A culture containing patterned cultured parenchymal cell spheroids which can be formed by culturing parenchymal cells on cultured endothelial cells or cultured fibroblasts which have been separated by a specific hydrophilic polymer surface and patterned. This culture can sustain a function specific to the parenchymal cells over a long period of time.

L'invention se rapporte à une culture contenant des sphéroïdes cellulaires cultivées à trame parenchymateuse qui peut être formée par la culture de cellules parenchymateuses sur des cellules endothéliales cultivées ou sur des fibroblastes cultivés qui ont été séparés au moyen d'une surface polymère hydrophile spécifique et structurée. Cette culture permet l'application d'une fonction spécifique aux cellules parenchymateuses sur une longue durée.

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