Curcuminoid compositions exhibiting synergistic inhibition...

Details Curcuminoid compositions exhibiting synergistic inhibition... Curcuminoid compositions exhibiting synergistic inhibition...

A - Human Necessities

61

K

A61K 31/365 (2006.01) A23K 1/16 (2006.01) A23L 1/29 (2006.01) A61K 31/12 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2454171

Compositions comprising an effective amount of a curcuminoid species and an effective amount of a diterpene lactone species, a triterpene species or derivatives thereof that have a synergistic effect on specific inhibition of inducible COX-2 activity and have minimal effect on COX-1 activity are disclosed. Methods of using the compositions for providing synergistic anti- inflammatory effects are also disclosed.

L'invention concerne des compositions qui comprennent une dose efficace d'une espèce de curcuminoïde et une dose efficace d'une espèce de lactone diterpène, une espèce de triterpène ou des dérivés de ceux-ci, qui ont un effet synergique sur l'inhibition spécifique de l'activité COX-2 inductible, tout en n'ayant qu'un effet minime sur l'activité COX-1. L'invention concerne également les utilisations de ces compositions pour la production d'effets anti-inflammatoires synergiques.

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