Cxcl10-based diagnosis and treatment of respiratory illnesses

G - Physics – 01 – N

Patent

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G01N 33/50 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61P 11/00 (2006.01) C12Q 1/00 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2478138

Elevated blood levels of the chemokine CXCL10 polypeptide are associated with respiratory illnesses (e.g. SARS, influenza and community-acquired pneumonia) and are useful in diagnosis of patients. Methods are provided for diagnosis and treatment of patients suffering from respiratory illnesses. Methods are provided for identifying inhibitors of the CXCL10:CXCR3 axis, for use in treating patients suffering from respiratory illnesses.

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