Cxcr4 agonist treatment of hematopoietc cells

Details Cxcr4 agonist treatment of hematopoietc cells Cxcr4 agonist treatment of hematopoietc cells

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 35/28 (2006.01) A61K 38/19 (2006.01) A61P 31/00 (2006.01)

Patent

CA 2305036

In accordance with various aspects of the invention, CXCR4 agonists may be used to treat bone marrow progenitor or stem cells to reduce the susceptibility of the cells to cytotoxic agents. CXCR4 agonists may be used to treat bone marrow progenitor cells or stem cells to reduce the rate of cellular multiplication. CXCR4 agonists may be used to treat cancer in a mammal in conjunction with one or more cytotoxic agents. Cytotoxic agents may for example include chemotheraputic agents or radiation. CXCR4 agonists may be used therapeutically to regulate bone marrow progenitor or stem cell growth in human diseases, such as cancer.

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