Cxcr4 antagonist treatment of hematopoietic cells

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/10 (2006.01) A61K 38/16 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) C07K 14/52 (2006.01)

Patent

CA 2408319

In accordance with various aspects of the invention, CXCR4 antagonists may be used to treat hematopoietic cells, such as progenitor or stem cells, to promote the rate of cellular multiplication, self-renewal, proliferation or expansion. CXCR4 antagonists may be used therapeutically to stimulate hematopoietic stem/progenitor cell multiplication/self-renewal.

L'invention concerne des antagonistes du CXCR4 qui peuvent être utilisés pour traiter des cellules hématopoiétiques, telles que des cellules souches ou progénitrices, afin de promouvoir la vitesse de multiplication, d'auto-renouvellement, de prolifération ou d'expansion cellulaire. Les antagonistes du CXCR4 peuvent être utilisés de manière thérapeutique pour stimuler la multiplication/l'auto-renouvellement de cellules souches/progénitrices hématopoiétiques.

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