Cyano phenylene-dioxamates

Details Cyano phenylene-dioxamates Cyano phenylene-dioxamates

C - Chemistry, Metallurgy

07

D

260/473.6

C07D 295/08 (2006.01) A61K 31/00 (2006.01) A61K 31/275 (2006.01) C07D 205/04 (2006.01)

Patent

CA 1058209

ABSTRACT OF THE DISCLOSURE It has now been discovered that novel compounds of Formula 1 Image wherein Image is at one of positions 4 or 5 and R1 and R2 are the same or different lower alkyl groups, are useful in the prophylactic treatment of sensitized humans and animals for allergy and all anaphylactic reactions of a reagin or non-reagin mediated nature. Additionally, the com- pounds are intermediates to the diacid or di salts which have utility in the same area as the esters. The compounds are formulated with pharmaceutical carriers for oral, parenteral, inhalation, or rectal means of administration.

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