C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 323/62 (2006.01) A61K 31/275 (2006.01) A61K 31/415 (2006.01) A61K 31/4402 (2006.01) A61K 31/4406 (2006.01) A61K 31/4409 (2006.01) C07C 255/29 (2006.01) C07D 211/20 (2006.01) C07D 213/32 (2006.01) C07D 213/83 (2006.01) C07D 231/12 (2006.01) C07D 233/54 (2006.01) C07D 233/64 (2006.01) C07D 235/06 (2006.01) C07D 257/04 (2006.01)
Patent
CA 2530068
This invention relates to a class of compounds having the general formula (I) which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.
L'invention se rapporte à une classe de composés ayant la formule générale (I) qui sont des inhibiteurs de la cystéine protéase, entre autres, des inhibiteurs de cathepsines K, L, S et B. Ces composés sont utilisés pour le traitement de maladies dans lesquelles l'inhibition de la résorption osseuse est indiquée, notamment l'ostéoporose.
Bayly Christopher
Black Cameron
Crane Sheldon
Mckay Daniel J.
Oballa Renata
Merck Frosst Canada Ltd.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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