Cyanoalkylpiperazines and methods for their preparation and use

Details Cyanoalkylpiperazines and methods for their preparation and use Cyanoalkylpiperazines and methods for their preparation and use

C - Chemistry, Metallurgy

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260/263, 260/267

C07D 295/14 (2006.01) C07D 239/42 (2006.01) C07D 295/15 (2006.01) C07D 401/12 (2006.01) C07D 403/04 (2006.01)

Patent

CA 1250580

CYANOALKYLPIPERAZINES AND METHODS FOR THEIR PREPARATION AND USE Abstract Cyanoalkylpiperazines are prepared by reacting piperazine with a haloalkylnitrile in the presence of an acid acceptor. The cyanoalkyl- piperazines are adventageously employed to prepare 1-(cyanoalkyl)-4-(2-pyrimidyl)piperazines by reacting them with halopyrimidines in the presence of an acid acceptor.

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