C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/02 (2006.01) A61K 31/4425 (2006.01) A61P 35/00 (2006.01) C07D 213/75 (2006.01)
Patent
CA 2485351
Pyridyl cyanoguanidine compounds of the general formula I wherein A, X1, X2, X3, Y1, Y2, Y3, R1, R2, R5, R6 and n are as indicated in the description are suitable as prodrugs in human and veterinary therapy of proliferative diseases such as cancers.
L'invention concerne des composés de pyridyle cyanoguanidine de formule générale I, dans laquelle A, X¿1?, X¿2?, X¿3?, Y¿1?, Y¿2?, Y¿3?, R¿1?, R¿2?, R¿5?, R¿6? et n sont tels que indiqués dans le descriptif et se prêtent à une utilisation comme promédicaments dans une thérapie à application humaine et vétérinaire de maladies prolifératives, notamment les cancers.
Binderup Ernst Torndal
Duvold Tore
Leo Pharma A/s
Osler Hoskin & Harcourt Llp
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