Cyanoguanidines and cyanoamidines as erbb2 and egfr inhibitors

Details Cyanoguanidines and cyanoamidines as erbb2 and egfr inhibitors Cyanoguanidines and cyanoamidines as erbb2 and egfr inhibitors

C - Chemistry, Metallurgy

07

D

C07D 239/94 (2006.01) A61K 31/4706 (2006.01) A61K 31/517 (2006.01) A61P 31/18 (2006.01) A61P 35/00 (2006.01) C07D 215/42 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/04 (2006.01)

Patent

CA 2506503

Cyanoguanidine quinazoline and cyanoamidine quinazolamine derivatives that are useful in the treatment of hyperproliferative diseases are disclosed. Use of the compounds of the invention to manufacture therapeutic compositions for the treatment of hyperproliferative diseases in mammals is also disclosed.

L'invention concerne l'utilisation de dérivés de cyanoguanidine quinazoline et cyanoamidine quinazolamine dans le traitement de maladies hyperproliférantes. L'invention concerne également l'utilisation de ces composés pour produire des compositions thérapeutiques destinées au traitement des maladies hyperproliférantes chez les mammifières.

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