Cyanomethylphenethanolamines

Details Cyanomethylphenethanolamines Cyanomethylphenethanolamines

C - Chemistry, Metallurgy

07

D

260/558.5, 260/3

C07D 209/12 (2006.01) A61K 31/05 (2006.01) A61K 31/13 (2006.01) A61K 31/135 (2006.01) A61K 31/275 (2006.01) A61K 31/295 (2006.01) A61K 31/395 (2006.01) A61K 31/40 (2006.01) A61K 31/405 (2006.01) C07D 209/04 (2006.01) C07D 209/14 (2006.01) C07D 209/18 (2006.01) C07D 209/20 (2006.01) C07D 209/40 (2006.01)

Patent

CA 1095525

Abstract of the Disclosure Preparation of cyanomethylphenethanolamines useful as adrenergic stimulants is described. Preferred compounds such as 2-hydroxy-5-[1-hydroxy-2-[(1,1-dimethyl-2-phenylethyl)amino]ethyl]- benzeneacetonitrile are selective beta-adrenergic stimulants having relatively greater potency on respiratory smooth muscle than on cardiac muscle. Such compounds are particularly valuable in the treatment of bronchial conditions.

276774

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