Cyanopyrrole-sulfonamide progesterone receptor modulators...

C - Chemistry – Metallurgy – 07 – D

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C07D 207/34 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) A61P 15/18 (2006.01) C07D 417/10 (2006.01)

Patent

CA 2612977

Progesterone receptor modulators of formula (I), or a pharmaceutically acceptable salt thereof, Formula (I); wherein R1, R2, R3, R4, R5, R6 and R7 are as defined herein, are useful for contraception and hormone replacement therapy are described. Also provided are products containing these compounds.

La présente invention concerne les modulateurs du récepteur de progestérone de la Formule I ou un sel de celle-ci pharmaceutiquement acceptable, la Formule :(I) ; dans laquelle R<SUB>1</SUB>, R<SUB>2</SUB>, R<SUB>3</SUB>, R<SUB>4</SUB>, R<SUB>5</SUB>, R<SUB>6</SUB> et R<SUB>7</SUB> sont tels que définis dans ladite formule, et sont utiles pour la contraception et pour la thérapie de remplacement d'hormone. Des produits contenant ces composés sont également fournis.

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