Cyclic amide derivatives

Details Cyclic amide derivatives Cyclic amide derivatives

C - Chemistry, Metallurgy

07

D

C07D 413/06 (2006.01) A61K 31/395 (2006.01) C07D 405/14 (2006.01) C07D 413/14 (2006.01) C07D 471/04 (2006.01) C07D 475/02 (2006.01) C07D 487/04 (2006.01) C07D 495/04 (2006.01) C07D 498/04 (2006.01)

Patent

CA 2175502

Cyclic amide derivatives defined by the formula: R1 - (CH2)n-Z (I) or a salt thereof are disclosed, in which R1 is a group derived from a substituted or unsubstituted cyclic amide compound, n is zero or an integer of 1 to 6 and Z is a group: Image in which R2 is an aryl, a halogen-substituted aryl, a cycloalkyl or a heterocyclic group, m is an integer of 1 or 2, R3 is hydrogen or a lower alkyl, R4 is an aryl or a halogen-substituted aryl, a cycloalkyl or a heterocyclic group, and p is an integer of 1 or 2, provided that when the cyclic amide compound is quinazolinone or quinazoline-dione, R2 aid R4 are neither aryl nor substituted aryl. The cyclic amide compounds are pharmacologically effective in the prevention and treatment of diseases due to insufficiency of the central choline functions.

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