Cyclic amine compounds and their production

Details Cyclic amine compounds and their production Cyclic amine compounds and their production

C - Chemistry, Metallurgy

07

D

167/211, 260/278

C07D 211/26 (2006.01) C07D 211/32 (2006.01) C07D 211/70 (2006.01) C07D 213/38 (2006.01) C07D 213/50 (2006.01) C07D 401/00 (2006.01) C07D 413/10 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2007553

Abstract 1. A cyclic amine compound of the formula Image wherein B means a saturated or unsaturated 5- to 7- membered aza-heterocyclic group which may be substituted; A means a bond or an alkylene or alkenylene group which may be substituted by hydrocarbon residues, oxo, hydroxyimino, and/or hydroxy, --- means either a single bond or a double bond (provided that when A means a bond, --- means a single bond); R2 and R3 independently mean a hydrogen atom or a hydrocarbon residue which may be substituted (provided that both of R2 and R3 are not hydrogen atoms) or jointly form a cyclic amino group together with the adjacent nitrogen atom, n is 0, 1 or 2 and p is 1 or 2 or a physiologically acceptable salt thereof. The compounds are useful for therapy of cerebral edema, acute symptoms in cerebral apoplexy and protection of brain and nerve cell, or useful as anticholinesterase or as brain function-improving agent.

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