Cyclic amine derivatives and uses thereof

Details Cyclic amine derivatives and uses thereof Cyclic amine derivatives and uses thereof

C - Chemistry, Metallurgy

07

D

C07D 207/20 (2006.01) A61K 31/40 (2006.01) A61K 31/44 (2006.01) A61K 31/4436 (2006.01) A61K 31/4545 (2006.01) A61K 31/4709 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) C07D 211/70 (2006.01) C07D 401/12 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2362077

Compounds represented by general formula (I), pharmaceutically acceptable salts and prodrugs of the same, or hydrates of them, which are useful as antiobestic drugs, preventive and therapeutic drugs for diabetes, or the like, wherein A is optionally substituted aryl or optionally substituted heteroaryl; X is O, S, NR (wherein R is hydrogen or lower alkyl), or a single bond; m is an integer of 0 to 4; n is an integer of 1 to 5; and p is an integer of 1 to 3.

L'invention porte sur des composés de formule générale (I), leurs sels pharmacocompatibles, et leurs précurseurs et hydrates utilisables comme médicaments contre l'obésité ou comme médicaments préventifs ou curatifs du diabète. Dans la formule (I) A est aryle ou hétéroaryle facultativement substitué; X est O, S, NR (R étant H ou alkyle inférieur) ou une liaison simple; m est un entier de 0 à 4; n est un entier de 1 à 5; et p est un entier de 1 à 3.

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