Cyclic amino compounds

Details Cyclic amino compounds Cyclic amino compounds

C - Chemistry, Metallurgy

07

D

C07D 211/72 (2006.01) A61K 31/395 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) C07D 205/04 (2006.01) C07D 205/08 (2006.01) C07D 207/12 (2006.01) C07D 211/52 (2006.01) C07D 211/54 (2006.01)

Patent

CA 2322171

A cyclic amino compound represented by the following formula: (see formula I) [wherein, R1 represents a substitutable phenyl group, R2 represents a substitutable aliphatic acyl group, a substitutable benzoyl group or an alkoxycarbonyl group, and R3 represents a substituted, saturated cyclic amino group which may optionally have a fused ring] or a pharmacologically acceptable salt thereof has excellent platelet aggregation inhibitory action and is useful as a preventive agent or remedy for embolism, thrombosis or arteriosclerosis.

L'invention concerne des composés amino cycliques représentés par la formule générale (I) ou des sels pharmacologiquement acceptables de ceux-ci, ayant, entre autres, une excellente activité anti-agrégation plaquettaire, et donc utiles en tant que remèdes et agents préventifs pour l'embolie, la thrombose ou l'artériosclérose. Dans la formule (I), R<1> représente phényle éventuellement substitué; R<2> représente acyle aliphatique éventuellement substitué, alcoxycarbonyle ou benzoyle éventuellement substitué; et R<3> représente amino cyclique saturé substitué et éventuellement fusionné au niveau du cycle.

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