Cyclic anthranilic acid carboxylic acid derivatives

Details Cyclic anthranilic acid carboxylic acid derivatives Cyclic anthranilic acid carboxylic acid derivatives

C - Chemistry, Metallurgy

07

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167/226, 260/281

C07D 215/48 (2006.01) A61K 31/47 (2006.01) C07D 215/50 (2006.01) C07D 215/52 (2006.01) C07D 471/06 (2006.01)

Patent

CA 2019200

Title of the Invention : Novel cyclic anthranilic acid carboxylic acid derivatives Abstract of the Invention: Cyclic anthranilic acid carboxylic acid derivatives of the following formula, Image wherein R1 is hydrogen atom, carboxyl group, lower alkoxy carbonyl group having 1 to 3 carbon atoms, or phenyl group which may be substituted, R2 and R4 are each independently a hydrogen atom, lower alkyl group having 1 to 3 carbon atoms or benzyl group, R3 is a hydrogen atom, halogen atom, nitro group, amino group, cyano group, carbamoyl group, carboxyl group, lower alkanoylamino group having 1 to 4 carbon atoms, benzoylamino group, lower alkylsulfonylamino group having 1 to 3 carbon atoms or phenylsulfonylamino group which may be substituted by methyl group; the acid addition or alkali salts thereof, are useful as drugs treat autoimmune diseases, antirheumatic agents and thera- peutic or prophylactic agents to treat metabolic bone diseases.

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