C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/243.25, 260/
C07D 215/48 (2006.01) C07D 265/36 (2006.01) C07D 279/16 (2006.01)
Patent
CA 1317294
Title of the invention : Novel cyclic anthranilic acid derivatives and process for their preparation Abstract of the invention : Cyclic anthranilic acid derivatives of the following formula, Image wherein R1, R2 and R3 each independently indicate a hydrogen atom, a halogen atom, lower alkyl group having 1 to 3 carbon atoms, lower alkoxy group having 1 to 3 carbon atoms, amino group, nitro group, hydroxy group, sulfonamide group, trifluoromethyl group, cyano group, carboxyl group, carbamoyl group, acetyl group, benzoyl- methyl group which may be substituted, methylthio group, phenyl- ethynyl group which may be substituted, ethynyl group which may be substituted, alkanoylamino group having 1 to 3 carbon atoms, benzoylamino group which may be substituted, alkylsulfonylamino group having 1 to 3 carbon atoms or phenylsulfonylamino group which may be substituted; R4 and R5 each independently indicate a hydrogen atom, lower alkyl group having 1 to 3 carbon atoms, cyano group, carboxyl group, hydroxymethyl group, phenyl group which may be substituted or benzyl group; R6 indicates a hydrogen atom, lower alkyl group having 1 to 3 carbon atoms or benzyl group; X indicates a methylene group, oxygen atom, sulfur atom, sulfinyl group or sulfonyl group; their acid or alkali salts thereof are useful as antirheumatoid agents. - 1 -
578918
Awano Katsuya
Fujimori Shizuyoshi
Kojima Eisuke
Borden Ladner Gervais Llp
Kyorin Pharmaceutical Co. Ltd.
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