Cyclic anti-inflammatory derivatives of...

C - Chemistry – Metallurgy – 07 – D

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C07D 307/78 (2006.01) A61K 31/335 (2006.01) C07D 307/79 (2006.01) C07D 307/83 (2006.01) C07D 407/10 (2006.01)

Patent

CA 1308110

CYCLIC ANTI-INFLAMMATORY DERIVATIVES OF DI-TERT-BUTYLPHENOL COMPOUNDS ABSTRACT OF THE DISCLOSURE The present invention involves compounds having the structure: Image , wherein (a) -A- is selected from the group consisting of -CH2-, Image , and -?-; (b) -Y is selected from certain low molecular weight alkyl chains which terminate in specific unsaturated functional groups: -C?CH, -?=CH2, -?=C=CH2 and aldehydes in the form of their acetals; pharmaceutical compositions comprising such compounds; and methods for treating inflammation by administering such compounds.

583746

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