Cyclic cadherin analogues comprising the sequence hav for...

Details Cyclic cadherin analogues comprising the sequence hav for... Cyclic cadherin analogues comprising the sequence hav for...

C - Chemistry, Metallurgy

07

K

C07K 14/705 (2006.01) A61K 38/17 (2006.01) A61M 25/00 (2006.01) C07K 7/64 (2006.01)

Patent

CA 2533781

Cyclic peptides comprising a cadherin cell adhesion recognition sequence HAV, and compositions comprising such cyclic peptides, are provided. Methods for using such peptides for modulating cadherin-mediated cell adhesion in a variety of contexts are also provided.

L'invention concerne des peptides cycliques comprenant une séquence HAV de reconnaissance de l'adhésion cellulaire médiée par la cadhérine, ainsi que des compositions comportant de tels peptides cycliques. L'invention concerne également des procédés d'utilisation de tels peptides pour la modulation de l'adhésion cellulaire médiée par la cadhérine dans toute une variété de contextes.

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