Cyclic compounds, their production and use

Details Cyclic compounds, their production and use Cyclic compounds, their production and use

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/55 (2006.01) C07D 471/14 (2006.01) C07D 487/04 (2006.01) C07D 487/14 (2006.01) C07D 491/147 (2006.01) C07D 495/14 (2006.01) C07D 498/04 (2006.01) C07D 498/14 (2006.01) C07D 513/14 (2006.01)

Patent

CA 2172421

Novel compounds of the following general formula or salts thereof. Image wherein Ring M is a heterocyclic ring having -N=C<, -CO-N< or -CS-N< as the partial structure -X ? Y<; Ra and Rb are bonded to each other to form Ring A, or they are the same or different and represent, independently, a hydrogen atom or a substituent on the Ring M; Ring A and Ring B represent, independently, an optionally substituted homocyclic or heterocyclic ring, and at least one of them is optionally substituted heterocyclic ring; Ring C is optionally substituted homocyclic or heterocyclic ring; Ring Z is an optionally substituted ring; and n represents an integer of from 1 to 6, or a salt thereof, which hasan excellent tachykinin receptor antagonistic effect, and their production, and pharmaceutical compositions.

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