C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/266.1, 260/2
C07D 241/08 (2006.01) C07C 271/22 (2006.01) C07D 403/04 (2006.01)
Patent
CA 1127641
ABSTRACT Compounds of the formula (I): Image characterised in that n is 1 to 5; L is CO2R wherein R is hydregen or CO2R is an ester group in which R contains from 1 to 12 carbon atoms, or CH2COR1 whereln R1 is C1-4 alkyl; Y is -CH2CH2-, CH=CH- or -C?C-; R2 is hydrogen or C1-4 alkyl; R4 is hydrogen or C1-9 alkyl, C3-8 cycloalkyl, C3-8 cyclalkyl-C1-6 alkyl; or R2 and R4 taken with the carbon atom to which they are joined represent a C5-8 cycloalkyl group; R5 is NR6R7 wherein R6 and R7 independently are hydro- gen, C1-4 alkyl, phenyl C1-4 alkyl or NR6R7 is a 3 to 7 membered heterocycllc group containing only one hetero atom; hydrogen, C1-4 alkyl or C1-4 alkyl substituted by an OH, C1-4 alkoxy, CN, halogen or NR6R7 group as defined above, or by one or two CO2A groups in which A is hydrogen or a group containing from 1 to 12 carbon atoms; and R8 and R9 independently are hydrogen, C1-4 alkyl or to- gether with the carbon atom to which they are joined are a C3-6 cycloalkyl group; and salts thereof, having activities similar to but more selective than those of natural prostaglandins, a process for their preparation and pharmaceutical compsoitions containing them.
333286
Beecham Group Limited
Borden Ladner Gervais Llp
LandOfFree
Cyclic diamides does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cyclic diamides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cyclic diamides will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-318177