Cyclic double hemiacetals of enediol compounds pocessing...

Details Cyclic double hemiacetals of enediol compounds pocessing... Cyclic double hemiacetals of enediol compounds pocessing...

C - Chemistry, Metallurgy

07

D

260/354.5

C07D 319/12 (2006.01) C07D 493/04 (2006.01)

Patent

CA 1167859

ABSTRACT OF THE DISCLOSURE Compounds of the general formula Image wherein R1 and R2 are hydrogen, alkyl, cycloalkyl, aryl or arylalkyl; R3 and R4 are singly hydrogen, alkyl or aryl and when taken together are Image OR Image wherein R5 through R10 are singly hydrogen, alkyl or aryl and R5 and R6 together can form =0 are disclosed. The com- pounds are useful as cytostatic, hypotensive and analgesic agents. A method of preparing these compounds by reacting a dialdehyde, an .alpha.-keto-aldehyde or diketone with an enediol or an acyloin is also disclosed.

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