Cyclic guanosine 3',5'-monophosphate phosphodiesterase...

Details Cyclic guanosine 3',5'-monophosphate phosphodiesterase... Cyclic guanosine 3',5'-monophosphate phosphodiesterase...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/505 (2006.01) A61P 15/00 (2006.01) C07D 231/00 (2006.01) C07D 235/00 (2006.01) C07D 239/00 (2006.01) C07D 253/00 (2006.01)

Patent

CA 2439528

Compound of general formula (I): wherein R1, R2, R3, R4, X, Y and R5 have the meanings given herein which are useful in the curative and prophylactic treatment of a medical condition for which inhibition of a cyclic guanosine 3',5'-monophosphate phosphodiesterase (e.g. cGMP PDE5) is desired.

L'invention porte sur un composé de la formule générale (I) dans laquelle R?1¿, R?2¿, R?3¿, R?4¿, X, Y et R?5¿ son tels que déterminés dans la demande. Ce composé est utile dans le traitement curatif et prophylactique d'un état médical dont on souhaite inhiber guanosine 3',5'-monophosphate phosphodiestérase (cGMP PDE5) cyclique.

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