Cyclic hexapeptides useful for increasing feed efficiency

C - Chemistry – Metallurgy – 07 – K

Patent

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530/7.64

C07K 7/64 (2006.01) A23K 1/16 (2006.01)

Patent

CA 1101843

ABSTRACT OF THE DISCLOSURE Synthetic novel cyclic hexapeptides having the structure: cyclo(D-Pro-Ala)3, cylco(D-Pro-Phe)3, cyclo(Pro-D- Phe)3, cyclo(Sar-Ala)3, cyclo(Pro-D-Ala)3, cyclo(Sar-Leu)3, cyclo(Sar-D-Phe) (Pro-D-Phe)2, cyclo(Pro-D-Leu)3, and cyclo(D-Pro-Leu)3 are prepared. Oral administration of these cyclic peptides improves the digestive efficiency of certain herbivorous animals.

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