Cyclic indole and heteroindole derivatives, the production...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 498/04 (2006.01) A61K 31/40 (2006.01) A61K 31/404 (2006.01) A61K 31/407 (2006.01) A61K 31/437 (2006.01) A61K 31/53 (2006.01) A61K 31/5395 (2006.01) A61K 31/549 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) C07D 209/12 (2006.01) C07D 209/14 (2006.01) C07D 409/06 (2006.01) C07D 471/04 (2006.01) C07D 471/14 (2006.01) C07D 487/04 (2006.01) C07D 498/14 (2006.01) C07D 515/04 (2006.01) C07D 515/14 (2006.01)

Patent

CA 2458399

The invention relates to novel substituted, annelated indole and heteroindole derivatives of general formula (I), to tautomers, stereoisomers, mixtures and pharmaceutically acceptable salts thereof and to the production and use thereof as medicaments, in particular as anti-tumour agents in mammals, in particular humans.

L'invention concerne de nouveaux dérivés substitués annelés d'indole et d'hétéroindole de formule générale (I), leurs tautomères, leurs stéréo-isomères, leurs mélanges et leurs sels pharmaceutiquement acceptables, ainsi que leur production et leur utilisation comme médicaments, en particulier comme antitumoraux, chez les mammifères, en particulier chez l'homme.

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