Cyclic inhibitors of carnitine palmitoyltransferase and...

Details Cyclic inhibitors of carnitine palmitoyltransferase and... Cyclic inhibitors of carnitine palmitoyltransferase and...

C - Chemistry, Metallurgy

07

D

C07D 211/58 (2006.01) A61K 31/17 (2006.01) A61K 31/397 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) A61P 3/10 (2006.01) A61P 35/00 (2006.01) C07C 275/32 (2006.01) C07D 205/04 (2006.01) C07D 207/50 (2006.01) C07D 211/56 (2006.01)

Patent

CA 2694724

A CPT1 inhibitor compound is represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof: or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. A method of treating a subject having cancer comprises administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof.

L'invention porte sur un composé inhibiteur de CPT1 qui est représenté par la formule structurelle (I) : ou sur un sel pharmaceutiquement acceptable de ce dernier. L'invention concerne une composition pharmaceutique qui comprend un composé représenté par la formule structurelle (I) ou un sel pharmaceutiquement acceptable de ce dernier. L'invention se rapporte également à un procédé qui permet de traiter un sujet souffrant d'un cancer en lui administrant une quantité thérapeutiquement efficace d'un composé représenté par la formule structurelle (I) ou d'un sel pharmaceutiquement acceptable de ce dernier.

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