C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 243/02 (2006.01) A61K 31/551 (2006.01) A61K 31/5513 (2006.01) A61P 25/00 (2006.01) A61P 25/24 (2006.01) C07D 243/14 (2006.01) C07D 243/24 (2006.01) C07D 401/04 (2006.01) C07D 403/04 (2006.01) C07D 405/04 (2006.01) C07D 405/10 (2006.01) C07D 409/04 (2006.01) C07D 409/10 (2006.01)
Patent
CA 2446696
The invention concerns novel benzodiazepinone derivatives and their uses in therapy particularly for treating pathologies involving the activity of a phosphodiesterase of cyclic nucleotides. The invention also concerns methods for preparing them and novel synthesis intermediates. The inventive compounds more particularly correspond to general formula (I).
L'invention concerne de nouveaux dérivés de type benzodiazépinones et leurs applications dans le domaine thérapeutique tout particulièrement pour le traitement de pathologies impliquant l'activité d'une phosphodiestérase de nucléotides cycliques. Elle concerne également des procédés pour leur préparation et de nouveaux intermédiaires de synthèse. Les composés de l'invention répondent plus particulièrement à la formule générale (I) :
Bourguignon Jean-Jacques
Klotz Eveline
Lagouge Yan
Lugnier Claire
Macher Jean-Paul
Neuro3d
Robic
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