Cyclic peptide antifungal agents

Details Cyclic peptide antifungal agents Cyclic peptide antifungal agents

C - Chemistry, Metallurgy

07

K

C07K 7/56 (2006.01) A61K 38/12 (2006.01) C07H 7/00 (2006.01) C07H 17/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2354056

A compound represented by structure (I) is described where R4 and/or R8 represent a sugar moiety. The compounds are shown to be useful as an antifungal and antiparatic agent or as an intermediate to such an agent. Methods of treatment and pharmaceutical formulations containing compounds represented by structure (I) are also described.

L'invention concerne un composé représenté par la formule (I), R?4¿ et/ou R?8¿ représentant une fraction de sucre. Ces composés sont utiles comme agent antifongique ou antiparasite ou comme intermédiaire de cet agent. L'invention concerne des techniques de traitement et des formulations pharmaceutiques renfermant ces composés.

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