C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/56 (2006.01) A61K 38/12 (2006.01) C07K 1/02 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2091663
Provided are compounds of the formula (1): see formula (1) wherein R' is hydrogen, methyl or NH2C(O)CH2-; R" is methyl or hydrogen; R is hydroxy or hydrogen; R1 is hydroxy, hydrogen, or hydroxysulfonyloxy; R7 is hydroxy, hydrogen, hydroxysulfonyloxy or phosphonooxy; R2 is a novel acyl side chain. Also provided are novel formulations, methods of inhibiting fungal and parasitic activity, and a process for preparing dideoxy (R=H) forms of the compounds.
Burkhardt Frederick Joseph
Debono Manuel
Nissen Jeffrey Scott
Turner William Wilson Jr.
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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