Cyclic peptide antifungal agents having a sugar substituent

Details Cyclic peptide antifungal agents having a sugar substituent Cyclic peptide antifungal agents having a sugar substituent

C - Chemistry, Metallurgy

07

K

C07K 7/56 (2006.01) A61K 38/12 (2006.01) A61P 31/10 (2006.01) A61P 33/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2354055

A compound represented by structure (I) is described where R8~ represents a sugar moiety. The compounds are shown to be useful as an antifungal and antiparasitic agent or as an intermediate to such an agent. Methods of treatment and pharmaceutical formulations containing compounds represented by structure (I) are also described.

L'invention concerne des composés représentés par la formule (I), R<8> représentant une fraction de sucre. Ces composés sont utiles comme agent antifongique et antiparasite ou comme intermédiaire de cet agent. L'invention concerne également des techniques de traitement et des formulations pharmaceutiques contenant les composés représentés par la formule (I).

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