Cyclic peptide cxcr4 antagonists

Details Cyclic peptide cxcr4 antagonists Cyclic peptide cxcr4 antagonists

C - Chemistry, Metallurgy

07

K

C07K 7/56 (2006.01) A61K 38/12 (2006.01) C07K 7/50 (2006.01) C07K 7/54 (2006.01) C07K 7/60 (2006.01)

Patent

CA 2688574

Provided are lactam-cyclized peptide CXCR4 antagonists useful in the treatment of cancers, rheumatoid arthritis, pulmonary fibrosis, and HIV infection.

L'invention concerne des antagonistes CXCR4 de peptides cyclisés par lactame, utiles dans le traitement des cancers, de la polyarthrite rhumatoïde, de la fibrose pulmonaire et de l'infection au VIH.

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