Cyclic peptides as potent and selective melanocortin-4...

Details Cyclic peptides as potent and selective melanocortin-4... Cyclic peptides as potent and selective melanocortin-4...

A - Human Necessities

61

K

A61K 38/12 (2006.01) C07K 5/037 (2006.01) C07K 7/56 (2006.01) C07K 14/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2396307

Cyclic peptides of formula (I) are potent and selective antagonists of melanocortin-4 receptors, and as such are useful research tool for the determination of the physiological roles of the MC-4 receptor, as well as for the diagnosis, treatment or prevention of disorders or diseases mediated through the MC-4 receptor.

Les peptides cycliques de la formule (I) sont des antagonistes puissants et sélectifs des récepteurs de la mélanocortine-4. Ils présentent une grande utilité comme outil de recherche pour déterminer les rôles physiologiques du récepteur MC-4 et permettent de diagnostiquer, traiter ou prévenir les troubles ou maladies induites par le récepteur MC-4.

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