A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/12 (2006.01) C07K 7/64 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2574605
A highly selective melanocortin-4 receptor antagonist cyclic hexapeptide of the formula: (I) where R1, R2, R3a, R3b, R4, R5, x, y and z are as defined in the specification, and a method of treating body weight disorders, including cachexia, sarcopenia and wasting syndrome or disease, and treating inflammation and immune disorders.
L'invention concerne un hexapeptide cyclique antagoniste du récepteur de la mélanocortine-4 hautement sélectif de la formule (I), dans laquelle R1, R2, R3a, R3b, R4, R5, x, y et z sont tels que définis dans le descriptif, ainsi qu'un procédé pour le traitement de troubles du poids, notamment la cachexie, la sarcopénie et le syndrome ou la maladie cachectique, ainsi que des troubles inflammatoires et immunitaires.
Burris Kevin B.
Rajpurohit Ramesh
Shadiack Annette M.
Sharma Shubh D.
Shi Yi-Qun
Palatin Technologies Inc.
Uren John Russell
LandOfFree
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