A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/12 (2006.01) C07K 7/64 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2573142
A highly selective melanocortin-4 receptor antagonist cyclic peptide of the formula where R1, R2, R3, R4a, R4b, R5, R6, R7, x, y and z are as defined in the specification, and a method of treating body weight disorders, including cachexia, sarcopenia and wasting syndrome or disease, and treating inflammation and immune disorders.
La présente invention a trait à un peptide cyclique antagoniste hautement sélectif du récepteur 4 de la mélanocortine de formule (I), dans laquelle: R1, R2, R3, R4a, R4b, R5, R6, R7, x, y et z sont tels que définis dans la description, et à un procédé de traitement de troubles de poids corporel, comprenant la cachexie, la sarcopénie et le syndrome ou la maladie de dépérissement, et le traitement de trouble inflammatoires et immuns.
Burris Kevin B.
Rajpurohit Ramesh
Shadiack Annette M.
Sharma Shubh D.
Shi Yi-Qun
Palatin Technologies Inc.
Uren John Russell
LandOfFree
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