Cyclic peptides having broad spectrum antimicrobial activity

Details Cyclic peptides having broad spectrum antimicrobial activity Cyclic peptides having broad spectrum antimicrobial activity

C - Chemistry, Metallurgy

07

K

C07K 7/64 (2006.01) A61K 38/12 (2006.01) A61K 38/16 (2006.01) A61L 2/16 (2006.01) C07K 14/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2261797

The present invention provides cyclic peptides having broad spectrum antimicrobial activity. The peptides exhibit improved efficacy, bioavailability and/or serum half-life as compared with non-cyclized analogues.

Cette invention concerne des peptides cycliques qui possèdent une activité antimicrobienne étendue. Ces peptides possèdent une efficacité, une disponibilité biologique et/ou une demi-vie sérique améliorées par rapport à leurs analogues non cyclisés

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