Cyclic peptides having melanocortin-4 receptor agonist activity

Details Cyclic peptides having melanocortin-4 receptor agonist activity Cyclic peptides having melanocortin-4 receptor agonist activity

C - Chemistry, Metallurgy

07

K

C07K 14/68 (2006.01) A61K 38/12 (2006.01) A61K 38/34 (2006.01) A61P 3/04 (2006.01) C07K 1/107 (2006.01) C07K 7/06 (2006.01) C07K 7/50 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2420058

The presente invention refers to peptides cyclized via disulfide or lactam bridges having melanocortin-4 receptor (MC4-R) agonist activity useful for treatment of obesity.

La présente invention concerne des peptides rendu cycliques par des passerelles disulfure ou lactame. Ces peptides, qui font preuve d'une activité agonsite du récepteur de la mélanocortine 4 (MC4-R), conviennent particulièrement pour le traitement de l'obésité.

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