Cyclic peptides having somatostatin activity

Details Cyclic peptides having somatostatin activity Cyclic peptides having somatostatin activity

C - Chemistry, Metallurgy

07

K

530/7.26, 530/7.

C07K 14/655 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1245638

Abstract of the disclosure: The invention relates to cyclic hexapeptides of the general formula III Image (III) in which X represents the radical of an L-aminoacid of the general formula IIIa Image (IIIa) in which A and B are identical or different and denote alkyl having 1 to 3 carbon atoms, or A and B together represent a saturated, unsaturated or aromatic monocyclic or bicyclic structure having 3 to 6 carbon atoms, n denotes 0 or 1, and Y represents an aliphatic or aromatic L-amino- acid the side chain of which can be hydroxylated, and their salts with physiologically tolerated acids, and to a process for their preparation and their use and their intermediates.

446519

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