Cyclic phosphites and phosphates

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 17/08 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2304058

Disclosed are the antibacterial compounds having formulas (I) or (II) or pharmaceutically acceptable salts and esters thereof. Also disclosed are the processes for preparing compounds of formulas (I), and (II) of the invention, pharmaceutical compositions comprising a therapeutically effective amount of a compound of the invention in combination with pharmaceutically acceptable carrier, as well as a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention.

L'invention concerne des composés antibactériens de formule (I) ou (II), ainsi que leurs sels et esters pharmaceutiquement acceptables. Elle concerne également des procédés permettant de préparer les composés de formule (I) et (II) de l'invention, des compositions pharmaceutiques renfermant une quantité, efficace sur le plan thérapeutique, d'un composé de l'invention, associé à un véhicule pharmaceutiquement acceptable, ainsi qu'une méthode permettant de traiter les infections bactériennes en administrant à un mammifère une composition pharmaceutique qui contient une quantité, efficace sur le plan thérapeutique, d'un composé de l'invention.

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