Cyclic polyamines

C - Chemistry – Metallurgy – 07 – D

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07D 471/08 (2006.01) A61K 31/395 (2006.01) A61K 31/675 (2006.01) C07D 273/00 (2006.01) C07D 471/18 (2006.01) C07D 519/00 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 2179530

Linked polyamine cyclic compounds of general formula V - R - A - R' - W where V and W are independently cyclic polyamine moieties having from 9 to 32 ring members and 3 to 8 amine nitrogens and having either one or more aromatic rings fused thereto or a heteroatom other than nitrogen incorporated in the ring, A is an aliphatic or aromatic moiety and R and R' are each a linking chain, possess improved partition coefficients at biologically relevant pH compared to known compounds, and possess high anti-HIV activity.

L'invention se rapporte à des composés cycliques de polyamines liées de la formule générale: V - R - A - R' - W dans laquelle V et W représentent indépendamment des fractions polyamine cyclique possédant des termes ayant de 9 à 32 cycles ainsi que 3 à 8 groupes azote amine, et possédant chacun un ou plusieurs noyaux aromatiques qui leurs sont additionnés, ou un hétéroatome autre que l'azote incorporé dans le noyau, A représente une fraction aliphatique ou aromatique et R et R' sont chacun une chaîne de liaison. Ces composés possèdent, par rapport aux composés connus, des coefficients améliorés de partage à un pH biologiquement approprié, et ils présentent une activité élevée contre le VIH.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Cyclic polyamines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cyclic polyamines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cyclic polyamines will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1354289

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.