Cyclic sulfamides for inhibition of gamma-secretase

C - Chemistry – Metallurgy – 07 – D

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C07D 417/10 (2006.01) A61K 31/433 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2503884

Compounds of formula I: inhibit the processing of APP by gamma-secretase, and hence are useful for treatment or prevention of Alzheimer's disease.

La présente invention concerne les composés représentés par la formule I, lesquels composés inhibent le traitement de la protéine précurseur amyloïde (APP) par la gamma-sécrétase et servent de ce fait au traitement ou à la prévention de la maladie d'Alzheimer.

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