Cyclic sulphenamide compounds, their production and their...

C - Chemistry – Metallurgy – 07 – D

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C07D 263/26 (2006.01) C07D 263/52 (2006.01) C07D 263/58 (2006.01) C07D 277/00 (2006.01) C07D 277/14 (2006.01) C07D 277/34 (2006.01)

Patent

CA 1183141

ABSTRACT OF THE DISCLOSURE The invention relates to cyclic sulphenamides of the formula Image wherein Z is oxygen or sulphur, R1 is an optionally substituted hydrocarbon group, and R2 to R5 are optionally substituted hydrocarbon groups which may be linked to the ring via an oxygen, sulphur or nitrogen atom, it being possible for two such radicals to form an additional bond in the ring or to be taken together to form an ylidene, spiro or fused substituent. The new cyclic sulphenamides are of use in medicine as lipoxygenase inhibitors.

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