Cyclic urea hiv protease inhibitors

Details Cyclic urea hiv protease inhibitors Cyclic urea hiv protease inhibitors

C - Chemistry, Metallurgy

07

D

C07D 403/00 (2006.01) A61K 31/55 (2006.01) A61K 38/05 (2006.01) C07D 243/04 (2006.01) C07D 401/00 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 405/00 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/00 (2006.01) C07D 409/14 (2006.01) C07D 413/00 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/00 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01) C07D 453/02 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01) C07D 475

Patent

CA 2215536

This invention relates to substituted cyclic ureas and derivatives thereof, including compounds of formula (II), said compounds being useful as inhibitors of HIV protease. The present invention also relates to pharmaceutical compositions comprising such compounds and to methods of using these compounds for the treatment of HIV infection. The present invention also relates to the use of such compounds in processes for the identification of HIV protease inhibitors and for the inhibition or detection of HIV in a bodily fluid sample.

Urées cycliques substituées et dérivés de ces urées renfermant des composés de la formule (II). Ces composés se révèlent utiles comme inhibiteurs de la protéase de VIH. L'invention porte également sur des compositions pharmaceutiques renfermant de tels composés et sur des procédés d'utilisation de ces composés dans le traitement de l'infection par VIH. L'invention porte également sur l'utilisation de ces composés dans des procédés d'identification d'inhibiteurs de la protéase de VIH et pour l'inhibition ou la détection du VIH dans un échantillon de liquide organique.

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