Cyclic vasoactive peptides

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/575 (2006.01) A61K 38/22 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2080272

The present invention relates to vasoactive peptide (VIP) analogs wherein the side chain carboxy terminus of one amino acid in the peptide chain is attached covalently to the side chain amino terminus of another amino acid in the peptide chain via the formation of an amide bond. The covalent bonding between the two amino acid residues in the peptide chain yields a ring structure. The present invention provides cyclic vasoactive peptides and pharmaceutical compositions comprising such a cyclic vasoactive peptide for the treatment of bronchotracheal constrictive disorders.

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