Cyclization to form cephem ring and intermediates therefor

Details Cyclization to form cephem ring and intermediates therefor Cyclization to form cephem ring and intermediates therefor

C - Chemistry, Metallurgy

07

D

260/242, 260/300

C07D 205/08 (2006.01) C07D 205/095 (2006.01) C07D 403/12 (2006.01) C07D 501/14 (2006.01)

Patent

CA 1095026

ABSTRACT OF THE DISCLOSURE Process for cyclizing compounds to give 3-hydroxy-3- cephem compounds, comprises cyclizing a compound of the formula: Image wherein A and B are, independently, hydrogen, substituted or unsubstituted alkanoyl, substituted or unsubstituted aralkanoyl, or substituted or unsubstituted aroyl; X is hydroxy or carboxy-protecting group and Hal is halogen.

337975

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