((cyclo)alkyl substituted)-gamma-aminobutyric acid...

Details ((cyclo)alkyl substituted)-gamma-aminobutyric acid... ((cyclo)alkyl substituted)-gamma-aminobutyric acid...

C - Chemistry, Metallurgy

07

D

C07D 257/04 (2006.01) A61K 31/41 (2006.01) A61K 31/66 (2006.01) C07C 233/36 (2006.01) C07C 239/14 (2006.01) C07C 259/06 (2006.01) C07D 271/06 (2006.01) C07D 271/07 (2006.01) C07D 285/08 (2006.01) C07D 285/18 (2006.01) C07D 291/04 (2006.01) C07F 9/38 (2006.01)

Patent

CA 2304965

Novel amines of formulas (1A) and (1B) are disclosed and are useful as agents in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, inflammatory diseases, and gastrointestinal disorders, especially IBS. Processes for the preparation and intermediates useful in the preparation are also disclosed.

L'invention concerne des nouvelles amines de formules (1A) et (1B), utiles en tant qu'agents dans le traitement de l'épilepsie, des crises de lipothymie, de l'hypocinésie, de troubles crâniens, de troubles neurodégénératifs, de la dépression, de l'anxiété, de la panique, de la douleur, de troubles neuropathologiques, d'affections inflammatoires et de troubles gastro-intestinaux, notamment du syndrome du côlon irritable. Des procédés de préparation et des nouveaux intermédiaires utiles dans la préparation sont également écrits.

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