Cyclo(hetero)alkenyl compounds useful for treating pain

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 417/14 (2006.01) A61K 31/4427 (2006.01) A61K 31/497 (2006.01) A61K 31/501 (2006.01) A61K 31/506 (2006.01) A61P 29/00 (2006.01) C07D 213/04 (2006.01) C07D 237/06 (2006.01) C07D 239/24 (2006.01) C07D 241/10 (2006.01) C07D 285/10 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/04 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2528920

A compound of formula: wherein Ar1, Ar2, V, X, R3, R4, and m are as disclosed herein or a pharmaceutically acceptable salt thereof (a "Cyclo(hetero)alkenyl Compound"); compositions comprising an effective amount of a Cyclo(hetero)alkenyl Compound; and methods for treating or preventing, e.g., pain, UI, an ulcer, IBD, or IBS in an animal, comprising administering to an animal in need thereof an effective amount of a Cyclo(hetero)alkenyl Compound are disclosed herein.

La présente invention a trait à un composé de formule (I), dans laquelle Ar?1¿, Ar?2¿, V, X, R¿3?, R¿4?, et m sont tels que définis dans la description, ou un de ses sels pharmaceutiquement acceptable (un <=composé cyclo(hétéro)alcényle>=) ; à des compositions comportant une quantité efficace d'un composé cyclo(hétéro)alcényle; et à des procédés pour le traitement ou la prévention de la douleur, de l'incontinence d'urine, d'un ulcère, de la maladie intestinale inflammatoire, ou du syndrome du côlon irritable chez un animal, comprenant l'administration d'un animal qui en a besoin d'une quantité efficace d'un composé cyclo(hétéro)alcényle.

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