C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/209, 260/241
C07D 487/08 (2006.01) A61K 31/55 (2006.01)
Patent
CA 1336514
The present invention provides a compound of formula I: Image (I) or a salt thereof, wherein: the dotted lines represent optional double bonds; R1 represents hydrogen, hydroxy, alkenyl, alkyl, aminoalkyl or hydroxyalkyl; R2 R3, R4, R5 and R6 independently represent hydrogen, hydroxy, fluoro, alkenyl, aryl, alkyl, or alkyl substituted with aryl, amino, hydroxy, carboxy or fluoro; and R7, R8, R9 and R10 independently represent hydrogen, hydrocarbon or a heterocyclic group provided that R7, R8, R9 and R10 are not simultaneously hydrogen; or R7 and R8 and/or R9 and R10 may complete a saturated or unsaturated C4-9 hydrocarbon or heterocyclic ring; which compounds are useful as anticonvulsant agents and in the treatment and/or prevention of neurodegenerative disorders.
584238
Baker Raymond
Carling William R.
James Kim
Leeson Paul D.
Merck Sharp & Dohme Limited
Swabey Ogilvy Renault
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